| Group | Club/Team Name | Team ID | Head Coach |
| L21 | Beach United FC - 01 BUFC Fusion U11/12 |
03022-001AG2U-0139 | Thuba Nkomazana |
| L22 | Bluffton Rush Soccer Club - 01 Bluffton Rush 2010 Girls |
03040-001AG2U-0019 | Dianne Wilson |
| L23 | Cainhoy Athletic Soccer Club CASC 10 Crusaders |
03006-001AG2U-2264 | Andrew Bergstrom |
| L24 | Cainhoy Athletic Soccer Club CASC 10 Tsunami |
03006-001AG2U-2248 | Gabriela Acosta |
| L25 | Charleston Soccer Club LLC CSC 10 Girls Navy North |
03034-001AG2U-0119 | Damon Dixon |
| L26 | James Island Youth SC JIYSC 2010 Girls Black |
03001-001AG2U-0111 | Lorne Walker |
| L27 | Mt. Pleasant SC - 01 MPRD Wildcats |
03007-001RG2U-0290 | Keith Lovas |
| L28 | South Carolina Surf Soccer Club SC Surf NA 10 Blue |
03008-001AG2U-0275 | Carlos Ortiz |